Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Milk Thistle Extract(Silybum marianum) (Fruit/Seed)(Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
**
Dandelion Root (Taraxacum officinale)
100 mg
**
Artichoke (Cynara scolymus) (Leaf)
50 mg
**
📅 Last updated:

Top Medical Research Studies

8
Flavonolignans reduce platelet activity
We aimed to explore how flavonolignans from silybum marianum, specifically silybin, silychristin, and silydianin, affect blood clotting through the COX pathway in platelets. Our methods involved analyzing platelet aggregation and the formation of COX pathway metabolites.

The findings were promising; these compounds showed a reduction in platelet aggregation and COX activity. Silychristin and silybin emerged as the most effective inhibitors, potentially acting as competitive blockers at the active COX site. This suggests that flavonolignans might offer new avenues for antiplatelet and anti-inflammatory therapies.
Read More
7
Silibinin shows promise for COVID-19
We explored silibinin from Silybum marianum as a potential treatment against SARS-CoV-2, focusing on its anti-inflammatory and anticoagulant effects. Through in silico analysis, we found that silibinin effectively binds to key viral proteins, suggesting it could inhibit the virus's entry and replication.

Our in vitro studies showed that silibinin also reduces expressions of proinflammatory genes linked to blood clotting. Overall, while silibinin shows promise, the need for more comprehensive clinical trials is crucial to fully understand its therapeutic potential against COVID-19.
Read More

Most Useful Reviews

7.5
Fatty liver treatment
8 people found this helpful
My liver was in a poor state due to fatty liver. After taking this, my blood test results returned to normal values. I don't feel the effects, but the data shows improvement. I took one after breakfast and dinner.
Read More
9
Improved liver values
1 people found this helpful
My liver values had always been high in blood tests, but after taking this, they returned to normal. Thank you!
Read More

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Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
  • All Researches
8
Flavonolignans reduce platelet activity
We aimed to explore how flavonolignans from silybum marianum, specifically silybin, silychristin, and silydianin, affect blood clotting through the COX pathway in platelets. Our methods involved analyzing platelet aggregation and the formation of COX pathway metabolites.

The findings were promising; these compounds showed a reduction in platelet aggregation and COX activity. Silychristin and silybin emerged as the most effective inhibitors, potentially acting as competitive blockers at the active COX site. This suggests that flavonolignans might offer new avenues for antiplatelet and anti-inflammatory therapies.
Read More
7
Silibinin shows promise for COVID-19
We explored silibinin from Silybum marianum as a potential treatment against SARS-CoV-2, focusing on its anti-inflammatory and anticoagulant effects. Through in silico analysis, we found that silibinin effectively binds to key viral proteins, suggesting it could inhibit the virus's entry and replication.

Our in vitro studies showed that silibinin also reduces expressions of proinflammatory genes linked to blood clotting. Overall, while silibinin shows promise, the need for more comprehensive clinical trials is crucial to fully understand its therapeutic potential against COVID-19.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Fatty liver treatment
8 people found this helpful
My liver was in a poor state due to fatty liver. After taking this, my blood test results returned to normal values. I don't feel the effects, but the data shows improvement. I took one after breakfast and dinner.
Read More
9
Improved liver values
1 people found this helpful
My liver values had always been high in blood tests, but after taking this, they returned to normal. Thank you!
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Speciale A, Muscarà C, Molonia MS, Cimino F, Saija A, et al. Silibinin as potential tool against SARS-Cov-2: In silico spike receptor-binding domain and main protease molecular docking analysis, and in vitro endothelial protective effects. Phytother Res. 2021;35:4616. 10.1002/ptr.7107
  2. Bijak M, Saluk-Bijak J. Flavonolignans inhibit the arachidonic acid pathway in blood platelets. BMC Complement Altern Med. 2017;17:396. 10.1186/s12906-017-1897-7
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